Prepare input files for molecular docking software, automatically determine Grid Box center and size. Supports AutoDock Vina, AutoDock4, and other mainstream docking tools.
Beautify meta-analysis forest plots with customizable odds ratio points and confidence intervals
Detect copy number variations from whole genome sequencing data and generate publication-quality genome-wide CNV plots. Supports CNV calling, segmentation, and visualization for cancer genomics and rare disease analysis.
Generate photorealistic rendering scripts for PyMOL and UCSF ChimeraX to create publication-quality molecular visualizations. Supports ray-tracing, depth of field, ambient occlusion, and cinematic lighting for journal covers and high-impact figures. Use for creating visually compelling protein structure images; not for routine structural analysis or measurements.
Generate interactive Krona charts (sunburst plots) for metagenomic samples to visualize taxonomic abundance hierarchies. Supports Kraken2, Bracken, Centrifuge output formats.
Check image DPI and intelligently upscale low-resolution images using super-resolution
Automatically label top significant genes in volcano plots with repulsion algorithm
Automatically assemble 6 sub-figures (A-F) into a high-resolution composite figure with aligned edges, unified fonts, and labels.
Convert complex Venn diagrams with more than 4 sets to clearer Upset plots
Performs GO (Gene Ontology) and KEGG pathway enrichment analysis on gene lists. Trigger when: - User provides a list of genes (symbols or IDs) and asks for enrichment analysis - User mentions "GO enrichment", "KEGG enrichment", "pathway analysis" - User wants to understand biological functions of gene sets - User provides differentially expressed genes (DEGs) and asks for interpretation - Input: gene list (file or inline), organism (human/mouse/rat), background gene set (optional) - Output: enriched terms, statistics, visualizations (barplot, dotplot, enrichment map)
Recommends appropriate statistical methods (T-test vs ANOVA, etc.) based on dataset characteristics, performs assumption checking, and provides power analysis guidance. Trigger when user asks about choosing statistical tests, checking statistical assumptions, or needs guidance on experimental design and sample size calculations.
Beautify phylogenetic trees with taxonomy color blocks, bootstrap values, and timeline annotations. Supports Newick format with customizable styling options.
Predict neoantigens that may be recognized by the immune system based on patient HLA typing and tumor mutation data. Trigger conditions: - User provides HLA typing results and mutation data, requesting neoantigen prediction - User inquires about tumor immunotherapy-related neoantigen prediction - Need to provide T-cell epitope prediction and immunogenicity assessment - Input: HLA alleles (HLA-A*02:01, etc.), tumor mutation data (VCF or peptide sequences) - Output: Predicted neoantigen list, HLA binding affinity, immunogenicity scores
Generate Circos configuration files for circular genomics data visualization. Supports genomic variations (SNPs, CNVs, structural variants), cell-cell communication networks, and custom track configurations for publication-ready circular plots.
Generate publication-quality sequence logos for DNA or protein motifs to visualize conserved positions and sequence patterns.
Detect image duplication and tampering in manuscript figures using computer vision algorithms
Convert between IUPAC names, SMILES strings, and molecular formulas for chemical compounds. Supports structure validation, identifier interconversion, and cheminformatics data preparation for drug discovery and chemical research workflows.
IoT monitoring simulation to predict CO2 tank depletion and prevent weekend gas outages in cell culture facilities. Monitors cylinder pressure, calculates consumption rates, and provides early warnings for timely replacement.
Calculate complex buffer recipes with precise measurements for molecular biology and biochemistry applications. Provides accurate mass/volume calculations, pH considerations, and step-by-step preparation instructions.
Calculate breeding timelines and cage requirements for transgenic mouse colonies
Automates abstract screening for systematic reviews and meta-analyses. Triggers when user needs to: screen multiple academic abstracts against inclusion/exclusion criteria, export PRISMA-compliant screening results, or generate screening reports with decision rationale. Supports batch processing of PubMed/EndNote/CSV formatted references with confidence scoring and conflict detection.
Automatically recommend ICD-10 diagnosis codes and CPT procedure codes from clinical notes. Trigger when: user provides clinical notes, patient encounter summaries, discharge summaries, or asks for medical coding assistance. Use for healthcare providers, medical coders, and billing professionals who need accurate code recommendations.
Convert physician verbal dictation into structured SOAP notes. Trigger when receiving audio/transcribed medical dictation, clinical encounter recordings, or unstructured clinical narratives requiring structured documentation. Supports real-time and batch processing of medical speech-to-text.
Audit medical device technical files against EU MDR 2017/745 regulations for compliance
Monitor bioRxiv/medRxiv preprints and academic discussions to identify emerging research hotspots before they appear in mainstream journals
Interprets complex biochemical laboratory test results and converts them into patient-friendly explanations. Trigger when: user provides lab test results (blood work, urine analysis, lipid panel, liver/kidney function tests, etc.) and needs plain-language interpretation of values, reference ranges, and clinical significance.
Check for drug-drug interactions between multiple medications. Trigger when user asks about medication compatibility, "can I take X with Y", drug interactions, contraindications, or safety of combining pharmaceuticals.
Generate CIOMS-compliant adverse event narratives for Individual Case Safety Reports (ICSR). Creates structured pharmacovigilance documents following CIOMS I and ICH E2B standards from case data for regulatory submission to health authorities.
Generate hospital discharge summaries from admission data, hospital course, medications, and follow-up plans. Trigger when user needs to create a discharge summary, compile inpatient medical records, or generate post-hospitalization documentation for patients.
Predict ADME (Absorption, Distribution, Metabolism, Excretion) properties for drug candidates using cheminformatics models and molecular descriptors. Evaluates drug-likeness, bioavailability, and pharmacokinetic profile to guide lead optimization and candidate selection in drug discovery.
Use when: User provides text/document and asks to check originality, detect plagiarism, assess similarity, or rewrite high-duplicate content. Triggers: "check plagiarism", "originality check", "similarity detection", "改写重复内容", "降重", "查重", "原创性检测", "抄袭检查" Input: Text content or document (txt, md, docx support via text extraction) Output: Originality score, highlighted duplicate/similar paragraphs, paraphrasing suggestions
Recommend suitable high-impact factor or domain-specific journals for manuscript submission based on abstract content. Trigger when user provides paper abstract and asks for journal recommendations, impact factor matching, or scope alignment suggestions.
Transform lengthy academic papers into concise, structured 250-word abstracts capturing background, methods, results, and conclusions. Optimized for research papers, theses, and technical reports across scientific disciplines.
Batch process chemical SMILES strings to remove salt ions and retain only active pharmaceutical ingredients
Draft prior authorization request letters for insurance companies with clinical justification. Trigger when user needs insurance pre-authorization for medical procedures, medications, or treatments requiring clinical documentation.
Search FDA industry guidelines by therapeutic area or topic. Trigger when user requests FDA guidance documents, regulatory guidelines, or asks about FDA requirements for specific disease areas, drug development, or therapeutic categories (e.g., oncology, cardiology, rare diseases). Also triggered by queries about FDA ICH guidelines, FDA guidance documents, or regulatory compliance requirements.
Grant proposal writing assistant for NIH (R01/R21), NSF and other mainstream funding applications. Triggers when user needs help writing specific aims, research strategy, budget justification, or other grant sections. Provides templates, section generators, and best practice guidance for competitive grant proposals.
Use when defining ArkType types, object schemas, optional/default properties, arrays, tuples, unions, intersections, string/number constraints, or built-in keywords.
Use when creating ArkType scopes, modules, cyclic/recursive types across definitions, submodules, private aliases, generics, or composing type namespaces.
Use when transforming data with ArkType pipes, morphs, .to(), .narrow(), .filter(), parse keywords like string.json.parse or string.numeric.parse, or the |> operator.
Use when handling ArkType validation errors, customizing error messages, using the traversal API (ctx.reject, ctx.mustBe), or configuring ArkType behavior globally or per-type.
Reliable, composable browser automation using minimal OpenCode Browser primitives.
This skill should be used when the user asks to "分析编译效率", "分析编译时间", "查看头文件依赖", "保存编译命令", "提取编译命令", "生成编译脚本", "保存这个文件的编译命令", "单独编译这个文件", "编译单个文件", "单编文件", "独立编译文件", "分析这个文件的头文件依赖", "头文件依赖关系", "这个文件依赖了多少头文件", "analyze compilation", "check header dependencies", "分析文件编译开销", "save compile command", "extract compile command", "generate compile script", "compile single file", "compile individual file", "standalone compile", "analyze header dependencies", "header dependency tree", "how many header files", or mentions analyzing compilation performance, build times, include dependencies, extracting/saving compilation commands, generating standalone compilation scripts, compiling individual files in isolation, or analyzing header file dependency relationships for specific source files in the ace_engine project. Provides comprehensive compilation efficiency analysis including timing, resource usage, dependency tree visualization with automatic saving, the ability to save reusable compilation scripts with performance monitoring, and standalone compilation capabilities using generated scripts.
Generate a summary of work from the previous workday. Collects git commits across all branches from local repositories and GitHub activity (issues, PRs, reviews) via gh CLI. Use when the user asks "what did I do yesterday", "summarize my work", "daily standup summary", or similar requests for a work recap.
RenderDoc GPU 帧分析与优化工具集。用于分析 RDC 抓帧文件,检测渲染管线中的性能问题与资源浪费。 触发场景: - 分析 RenderDoc 抓帧文件 (.rdc) - 检测 Shader 资源绑定浪费 (SRV/UAV/CBV 未使用) - 检测顶点属性浪费 (下发但未被 VS 使用的属性,如 TANGENT/BINORMAL) - 分析 Draw Call 带宽消耗 - Android 设备远程分析 (通过 ADB + Remote Server) - GPU 过度绘制检测 - Render Pass 依赖分析 - 内存使用统计
ACE-Step documentation and troubleshooting. Use when users ask about installing ACE-Step, GPU configuration, model download, Gradio UI usage, API integration, or troubleshooting issues like VRAM problems, CUDA errors, or model loading failures.
設計判断・デバッグ・レビューを Codex CLI に委譲する。
Secure credential management for trading platforms
Add a character to a party. Usage: /recruit <name|alignment> [class] [--persona text] [--role label] [--party name]
Downloads and archives X (Twitter) posts, articles, and threads as structured Markdown with media. Supports single and batch download with anti-detection measures. Use when the user wants to save, download, archive, or convert X/Twitter posts to Markdown. Triggers: "download tweet", "save this X post", "archive this tweet", "convert tweet to markdown", "batch download tweets", or when user provides x.com / twitter.com URLs and asks to save/download them.
Remove a character from a party. Usage: /dismiss <name|index|role> [--party name]
Manage adventuring parties. Create, list, show, delete, and set active party.
> 在 Windows PowerShell/CMD 环境下操作 SQLite 数据库的避坑指南
Prove properties about rings, ideals, and quotient rings. Work with prime and maximal ideals, quotient constructions, and ring homomorphisms. Triggers on "ideal", "quotient ring", "prime ideal", "maximal ideal", "ring homomorphism", "R/I", "principal ideal"
Prove properties about group homomorphisms, kernels, images, and isomorphisms. Use the First Isomorphism Theorem and properties preserved under homomorphisms. Triggers on "homomorphism", "kernel", "image", "isomorphism theorem", "quotient group", "normal subgroup", "group map"
Comprehensive code review with distinct aspect based sections. Use when reviewing code, checking for security issues, finding type safety problems, auditing code quality, or when user asks to review code, PRs or changes. Three-phase workflow runs static tools, LLM judgment, and writes diagnostic log.
Create consistent session handoff documents for context transfer between sessions. Use when closing a session, reaching 75% token consumption, or when user requests handoff. Ensures proper YAML headers for metrics collection, LF line endings, and complete documentation of progress, decisions, and next steps.
Per-component-type verification approaches. Use when generating verification scripts for different component types.
Configure a multi-line status bar for Claude Code. Supports init, preset switching, and customization.
Manage Things 3 via the `things` CLI on macOS (add/update projects+todos via URL scheme; read/search/list from the local Things database). Use when a user asks Clawdbot to add a task to Things, list inbox/today/upcoming, search tasks, or inspect projects/areas/tags.
Manage Apple Reminders via the `remindctl` CLI on macOS (list, add, edit, complete, delete). Supports lists, date filters, and JSON/plain output.
Clean and organize Desktop, Downloads, and common clutter folders by file type. Use when user wants to declutter workspace, organize files by category, analyze disk usage, or clean up old files. Categorizes documents, images, videos, code, and more automatically.
CLI to manage emails via IMAP/SMTP. Use `himalaya` to list, read, write, reply, forward, search, and organize emails from the terminal. Supports multiple accounts and message composition with MML (MIME Meta Language).
Interact with the QR Coin auction platform on Base blockchain (qrcoin.fun).
Effect patterns for Schema, errors, services, layers, Match, data. Use for Effect code and APIs.
Claude Code configuration: skills, agents, hooks, commands creation. MCP servers setup, IDE integrations (VS Code, JetBrains, Vim). Settings, permissions, memory. Naming conventions, directory structure, best practices.
Guides the creation of high-quality Skills for the Antigravity agent environment. Use when the user requests to create a new skill, build a skill system, or needs guidance on skill architecture and best practices.
Python project workflow and standards using Astral uv for environments/dependencies, ty for type checking, typer for CLI, ruff for lint/format, pytest and pytest-cov for tests/coverage, and loguru for logging. Use for Python 3.12+ project setup, dependency management, CLI/logging patterns, type checking, testing, linting/formatting, and packaging guidance.
Configure MCP server with OAuth for SharePoint/OneDrive access on Foundry agents. Use when asked to set up SharePoint/OneDrive MCP integration.
Inspect Redis cache keys, values, and TTLs for debugging. Supports both main cache and system cache. Use for debugging cache issues, checking cached values, and monitoring cache state. Read-only by default.
Manage Next.js dev servers across worktrees. Start, stop, and read logs from dev servers. Agents can access logs from any running session, regardless of who started it.
Generate a new article on a topic. Content is published directly.
Test and automate TUI applications using tuistory (Playwright for terminals). PREFERRED over tmux-tui for most cases. Use when you need reliable TUI automation with proper wait conditions instead of sleep hacks.
Orchestrates a complete, standardized workflow for preparing a pull request in the VChart project. Use this skill to run a sequence of tasks: automated testing, changelog generation, smart commit, PR body creation, and PR submission. It provides a fixed 5-step process with manual checkpoints, ensuring quality and consistency for every contribution.
Creates a GitHub Pull Request for the VChart project using a local markdown file as its body. This skill exclusively uses a logged-in `gh` CLI environment to operate.
Bootstrap repos with just command runner. Use when setting up new projects, creating justfiles, or adding task automation. Provides ./dev bootstrap script that installs just, modular justfile structure in just/ directory, and recipe conventions.
Create GitLab issues through conversational brainstorming. Use when user wants to capture ideas, features, bugs, or work items as GitLab tickets. Supports linking related issues, label management, and iterative refinement through dialogue.
Contract 创建和检查(确保 Contract 质量和规范性)
iOS TestFlight リリース自動化。「TestFlightにリリース」「iOSリリース」「TestFlightアップロード」と言われたときに使用。
Quick reference for Nix + Home Manager commands and patterns. Use for package management and dotfiles configuration.
Reference Pydantic documentation and source for code improvement
Reference documentation for PDBx/mmCIF dictionary queries and category lookup
Plans detailed volume outlines with chapter-by-chapter breakdown, cool-point distribution, and Strand Weave pacing. Activates when user requests outline planning or /webnovel-plan.
Use when about to claim work is complete, fixed, or passing, before committing or creating PRs - requires running verification commands and confirming output before making any success claims; evidence before assertions always
Look up Microsoft API references, find working code samples, and verify SDK
Use when automating browsers, testing pages, taking screenshots, checking UI, verifying login flows, or testing responsive behavior
Read, write, and navigate the project filesystem
Use this skill for reinforcement learning tasks including training RL agents (PPO, SAC, DQN, TD3, DDPG, A2C, etc.), creating custom Gym environments, implementing callbacks for monitoring and control, using vectorized environments for parallel training, and integrating with deep RL workflows. This skill should be used when users request RL algorithm implementation, agent training, environment design, or RL experimentation.
使用 AI 理解和分析多媒体内容(图片、视频、音频)。Use when user wants to 理解图片, 分析视频, 音频转文字, 视频问答, understand media, analyze video, transcribe audio, describe image, what is in this video/image/audio.
勤怠の集計ロジック(労働時間、休憩控除、遅刻早退、残業、端数処理)を仕様化し、実装・テスト可能な形に落とす時に使う。
Generate architecture diagrams as .excalidraw files from codebase analysis. Use when the user asks to create architecture diagrams, system diagrams, visualize codebase structure, or generate excalidraw files.
Tag Zotero items with timestamp tags after generating bibliographies. Uses secure macOS Keychain storage for credentials. Claude Code only.
Tidy evaluation and programmatic tidyverse patterns using rlang. Use this skill when writing functions that accept column names as arguments, building tidyverse-compatible APIs, or working with data-masking and injection operators. Covers embracing with {{}}, injection (!! and !!!), dynamic dots, .data/.env pronouns, name injection with glue syntax, bridge patterns between selection and data-masking, and package development with rlang.
Comprehensive document creation, editing, and analysis with support for tracked changes, comments, formatting preservation, and text extraction. When Claude needs to work with professional documents (.docx files) for: (1) Creating new documents, (2) Modifying or editing content, (3) Working with tracked changes, (4) Adding comments, or any other document tasks
Efficiently search the web and scrape pages using local SearXNG + Crawl4AI services, with natural language responses and optional compression
Markdown to HTML to PowerPoint presentation converter using html2pptx library. Use when creating slide presentations from markdown content, generating HTML slides with strict layout constraints for PPTX conversion, or building PowerPoint files from HTML templates. Triggers on requests to create presentations, slides, PPTX files, or convert markdown to slides.
LSP (Language Server Protocol) 服務。支援 Daemon 常駐模式與即時語法診斷。用於獲取精確型別資訊、函數定義、符號引用、語法錯誤。目前支援 Python (basedpyright)。
Build iOS Release configuration for simulator. Use when building the app for testing, preparing release builds, or before running Maestro tests.
Create tickets in the mip-mobile-app ticket system. Use when the user asks to create a ticket, add a task, or track work items for this project.
グロースパック for LINEのデモを構築する。プロジェクト作成から実装まで一貫して行う。Next.js 14+ App Router、Tailwind CSS、Framer Motion環境を構築し、ドキュメントに基づいてLINEミニアプリとデモ環境を実装。使用タイミング: (1)デモを構築して (2)デモ用のプロジェクトを作成して (3)プロトタイプガイドを元にデモを実装して (4)LINEミニアプリのデモ環境を作って