Predict neoantigens that may be recognized by the immune system based on patient HLA typing and tumor mutation data.
Trigger conditions:
- User provides HLA typing results and mutation data, requesting neoantigen prediction
- User inquires about tumor immunotherapy-related neoantigen prediction
- Need to provide T-cell epitope prediction and immunogenicity assessment
- Input: HLA alleles (HLA-A*02:01, etc.), tumor mutation data (VCF or peptide sequences)
- Output: Predicted neoantigen list, HLA binding affinity, immunogenicity scores